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Type 2 diabetes patients taking Ozempic and Wegovy may be getting an unexpected benefit: a little more courage.
A new study suggests that semaglutide, the active ingredient in hit weight-loss drugs, could help strengthen bones in those with type 2 diabetes, even while shedding pounds, according to a report in Science Daily.
Researchers found that patients with type 2 diabetes taking semaglutide were 15% less likely to suffer bone fractures than patients using other popular weight-loss medications.
This is a surprising turn, as many experts were concerned that rapid weight loss could leave bones more brittle.
Semaglutide users not only lost more weight than patients taking competing treatments, but they also appeared to be less likely to break a bone, said the researchers, led by Dr.
Jairo Noreña, a former endocrinology fellow at Stanford University Medical Center in Palo Alto, California.
The research team examined the medical records of more than 59,000 adults with type 2 diabetes.
Among the 26,324 semaglutide users, the researchers recorded 794 fractures.
The comparison group (33,555 patients taking other weight-loss medications) suffered a whopping 1,045 fractures.
The findings were released at ENDO 2026, the Endocrine Society's annual meeting in Chicago, which took place June 13-16.
The conference brought together thousands of professionals in hormonal science and medicine.
The findings have real-world implications, particularly for the millions of older adults taking weight-loss medications who may already be at risk for bone loss.
"Bone fractures are painful, costly and can seriously affect quality of life, especially as people age," Noreña said.
"We hope this study encourages monitoring of bone health in weight loss programs.
This work is an important first step toward understanding the impact of semaglutide-induced weight loss on bone health in patients with type 2 diabetes."
A new study suggests that semaglutide, the active ingredient in hit weight-loss drugs, could help strengthen bones in those with type 2 diabetes, even while shedding pounds, according to a report in Science Daily.
Researchers found that patients with type 2 diabetes taking semaglutide were 15% less likely to suffer bone fractures than patients using other popular weight-loss medications.
This is a surprising turn, as many experts were concerned that rapid weight loss could leave bones more brittle.
Semaglutide users not only lost more weight than patients taking competing treatments, but they also appeared to be less likely to break a bone, said the researchers, led by Dr.
Jairo Noreña, a former endocrinology fellow at Stanford University Medical Center in Palo Alto, California.
The research team examined the medical records of more than 59,000 adults with type 2 diabetes.
Among the 26,324 semaglutide users, the researchers recorded 794 fractures.
The comparison group (33,555 patients taking other weight-loss medications) suffered a whopping 1,045 fractures.
The findings were released at ENDO 2026, the Endocrine Society's annual meeting in Chicago, which took place June 13-16.
The conference brought together thousands of professionals in hormonal science and medicine.
The findings have real-world implications, particularly for the millions of older adults taking weight-loss medications who may already be at risk for bone loss.
"Bone fractures are painful, costly and can seriously affect quality of life, especially as people age," Noreña said.
"We hope this study encourages monitoring of bone health in weight loss programs.
This work is an important first step toward understanding the impact of semaglutide-induced weight loss on bone health in patients with type 2 diabetes."
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